ADU selectively binds to A fibrils and soluble oligomers, which reduced amyloid plaques in a dose-dependent and time-dependent manner ( Box 2 )
Caloric restriction and L-carnitine administration improves insulin sensitivity in patients with impaired glucose metabolism 40
The antioxidant functions of glutathione in its reduced form include recycling vitamins E and C and serving as a critical free radical scavenger in all types of tissues, especially the liver
Deploying these nanoparticles ensures localized and controlled induction of ICD within the TIME, minimizing systemic toxicity while enhancing antitumor immunity [78,79,80]
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Funding Statement We appreciate the funding support from the NIH-NHLBI (2R15HL143545-02)