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The only reliable way to preserve muscle mass during rapid weight loss is adequate protein intake combined with resistance training

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Eight DEGs involving proteins were presented in purine/pyrimidine metabolism, among which the nucleoside diphosphate kinase (Ndk) is a housekeeping enzyme that functions to balance the cellular nucleoside triphosphate pool and was believed to regulate microbial virulence [72], showed a value of log2FC 2.80 at 3 DPI vs CK (Additional file 1: Dataset S1)

4c and Extended Data Fig

And remember, this result came from the shorter trial