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Those who experienced severe GI side effects on tirzepatide or semaglutide that required treatment discontinuation should proceed with extreme caution, as the combination will likely produce similar or potentially more pronounced effects

It may also help reduce fatigue and mental fog, making it easier to stay active and focused on lifestyle changes

R., Todorov, P., Kraleti, S., & Le, T

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conditions like irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), or reflux could be at play