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Constipation occurs because prolonged colonic transit time increases water absorption from stools, making them harder and more difficult to pass

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Clinical trials have shown promising results for both medications, but individual responses may vary

Abdominal discomfort from slowed gastric emptying can overlap with pelvic pressure from a bladder infection

HDL-C, high-density lipoprotein cholesterol

This medication is also used to help lower the risk of various cardiovascular diseases and worsening kidney disease (in patients with chronic kidney disease and type 2 diabetes)