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A landmark crossover study utilizing Magnetic Resonance Imaging (MRI) meticulously assessed muscle disruption following a heavy physical exertion protocol

doi: 10.1210/jc.2007-2350 47 HedmanCAFrystykJLindstromTChenJWFlyvbjergAOrskovHet al

On the one hand, excess iron ions can directly catalyze ROS production, exacerbating oxidative stress, while also promoting the generation and aggregation of A and catalyzing the hyperphosphorylation of the tau protein

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doi:10.1038/npp.2008.152