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In total, 7187 (9.8%) participants had a major adverse cardiovascular event, including 268 (3.7%) who were receiving GLP-1 receptor agonist and 6919 (96.3%) who were not receiving a GLP-1 receptor agonist at baseline

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Retatrutide is an investigational triple receptor agonist (GLP-1, GIP, and glucagon) not yet licensed by the MHRA or EMA for use in the UK

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