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The investigators concluded that administration of exogenous GSH had a beneficial effect on renal function by virtue of its antioxidant properties, and possibly by a vasodilator action to increase the glomerular filtration rate as well

Hall, K

Shim, E

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Namely, proteinprotein and protein-DNA interactions are disrupted by GST tag crosslinking, which results in functional inactivation of the fused protein

In vitro studies using MDCK cells (a model of intestinal epithelial permeability) demonstrated that PLGA nanoparticles significantly enhanced cellular uptake and transport of puerarin across cell monolayers, achieving a permeability coefficient value of 2.83 0.27 10 5 cm/s, which was significantly higher than that observed for free puerarin (0.38 0.07 10 5 cm/s)