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As HFpEF is a complex and multifactorial disease and therefore a more targeted treatment based on individual comorbidities, it may change the natural history of the disease [57]
Neurophysiology of gait
The percentage of recycled receptor was calculated by subtracting residual median fluorescence following the recycling protocol from that measured at t = 15 min, and normalizing to the percentage of internalized receptor at the same t = 15 min time-point
This intervention resulted in reduced microglia activation and lowered expression of downstream inflammatory cytokines IL-1 and TNF- in the peri-infarction regions (Gao et al., 2022)
Ethics approval was not required for this literature review as it did not involve any primary research with human subjects
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