50.0 50.1 Rosen CJ, Ingelfinger JR (2026)
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Compared with other organs in the body, the brain consumes more oxygen, generates more free radicals, has a higher concentration of polyunsaturated fatty acids, and a lower level of antioxidants, and is therefore more susceptible to damage caused by oxidative stress ( Figure 1 Oxidative stress damage may be linked to schizophrenia mechanisms Social isolation, vitamin D deficiency, chronic stress during adolescence, perinatal infections, inflammation, etc.-all of which ultimately lead to oxidative stress ( Figure 2 )
doi: 10.1080/02713680802123532 42 TsaiCCWuSBChengCYKaoSCKauHCChiouSHet al
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These compounds have been investigated for the treatment of rheumatoid arthritis, renal injuries, gastric cancer, lung cancer, and other diseases (Yang et al., 2023)
