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The dual approach also improved insulin sensitivity beyond what GLP-1 monotherapy delivered in SURPASS-2

[4] [7] Importantly, GLP-1 receptor agonists do not directly affect thyroid hormone production or metabolism

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Kaplan-Meier curves demonstrating lower cumulative incidence of overall cancer among GLP-1RA initiators (blue line) compared with matched nonusers (orange line) during up to 8 years of follow-up

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