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The cellular reduction of LA to DHLA is accomplished by NAD(P)H-driven enzymes, thioredoxin reductase, lipoamide dehydrogenase, and glutathione reductase

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FIGURE 3 Effect of GA on drug-induced liver injury (DILI) The phenotype of DILI is intricate, encompassing nearly all presently recognized forms of liver injury, ranging from mild, asymptomatic elevations in liver biochemical markers to jaundice, acute liver failure, and in the most severe cases, fatality ( Diclofenac (DIC) is a non-steroidal anti-inflammatory medicine commonly used for treating rheumatoid arthritis pain