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The connection between magnesium deficiency and chronic fatigue has been documented for decades

doi: 10.1016/j.cell.2016.12.022 49 van der LeunAMThommenDSSchumacherTN

So this isnt really a good cut-off, because half of the women who are pregnant at 100 IU/L wont have a clinical pregnancy (ie

From a health economics perspective, lifelong B12 supplementation should involve cost-effective delivery routes and tailored dosages to optimise clinical outcomes while minimising excess