Smoking cessation: Bupropion acts on the nucleus accumbens and the prefrontal cortex, areas of the brain that control cravings and reward stimulation
However, the FDA prescribing information includes a warning about acute kidney injury (AKI) in patients who experience severe gastrointestinal adverse reactions
As with any economic evaluation of long-term chronic diseases, a limitation of this analysis is the use of short-term clinical data to simulate the course of the disease over a 40-year time horizon
Adding the dehydration and constipation effects of semaglutide to an already vulnerable system requires proactive prevention, not reactive treatment
As a single-site analysis of a self-enrolled commercial cohort, the population may not fully represent the broader diversity of individuals with obesity, particularly those with limited access to digital tools or private care settings
They were randomly assigned to receive either 2.0 mg or 1.0 mg of once-weekly semaglutide