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Pasireotide drastically inhibited GLP-1 secretion induced by Gs-coupled receptor stimulation through SSTR5-Gi-dependent inhibition of cAMP levels, suggesting that the main pathway was completely blocked

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of injectable medications used primarily for managing type 2 diabetes and, in some formulations, for weight management

It is widely accepted that CD is predominantly propelled by a Th1-mediated response, whereas UC is linked to an atypical Th2 response [216]

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