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Food and Drug Administration, 2022

Indeed, the inhibition of GT or cysteine S -conjugate -lyase (both highly expressed in proximal tubule cells of the kidney) blocks the nephrotoxicity of cisplatin in mice (Townsend et al., 2003)

These strategies address both the physical and psychological aspects of fatigue management

Below, we summarize novel therapeutic targets and strategies with clinical application potential to provide more options for disease treatment (Table 1)