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According to the NHS, taking folic acid supplements can sometimes mask the signs of a B12 deficiency

Higher B12 has been associated with reduced kidney function in population data, particularly among individuals with higher homocysteine concentrations

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[18] Additionally, very high doses of folic acid could potentially mask a B deficiency, so its important your doctor knows about any folate supplements you take

Pregnant or breastfeeding women, people with copper metabolism disorders like Wilsons disease, and anyone with active skin infections should speak with a doctor before starting