Behavioral intervention for the treatment of obesity: strategies and effectiveness data
[39] In some models, adjusting the dose amount kept nearly 100% of the weight loss even at half the frequency
This promotes the market growth
Despite these beneficial metabolic effects, native GLP-1 has significant pharmacokinetic limitations that restrict its therapeutic utility
Additionally, side effects of GLP-1 medications, like nausea and vomiting, can prompt dehydration (and dry mouth), enamel erosion, tooth sensitivity, and discoloration
Over timeparticularly as patients transition from the active-weight-loss phase to long-term maintenancethe psychological burden of ongoing injections can become more apparent, Akshay Jain, a clinical instructor at the University of British Columbia, told me