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Herein, we reviewed the regulatory mechanisms of ferroptosis, summarized the recent findings associated with the involvement of ferroptosis in DKD, and discussed the potential of ferroptosis as a promising target for DKD treatment, thereby providing a valuable reference for basic study and clinical therapy of DKD

Glutathione is often referred to as the "master antioxidant" due to its ability to regenerate other antioxidants in the body

Chan, P., Shao, L., Tomlinson, B., Zhang, Y

It is worth noting that the evolution of Ca 2+ signaling dates back to prokaryotes, making it an important intracellular messenger regulating multiple cellular functions in all domains of life [193,194,195]

doi: 10.1111/jgh.12019 53