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Because these processes can emerge earlier or be more pronounced in people with HIV, this community can help us identify interventions that may improve healthspan more broadly. In a related pilot study published in npj Aging last month, Corley and another team of researchers found that taking semaglutide for 24 weeks: Reduced the rate of biological aging for 42% of participants with HIV and metabolic dysfunction-associated steatotic liver disease (MASLD) also known as fatty liver disease as measured by the DunedinPACE epigenetic clock
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For both uses, it is recommended to combine these medications with diet and exercise to produce long-lasting results
Gilron I, Robb S, Tu D, Holden R, Towheed T, Ziegler D, Wang L, Milev R, Gray C (2021) Double-blind, randomized, placebo-controlled crossover trial of alpha-lipoic acid for the treatment of fibromyalgia pain: the IMPALA trial
[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Kaczmarek A., Vandenabeele P., Krysko D.V