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AstraZeneca supported its supplemental application with data from the Phase III AEGEAN study, in which the Imfinzi regimen elicited a 17.21% pathological complete response rate, compared to 4.28% in the placebo arm
N., Davis, H., Buckler, K
One 2024 study at the Smell and Taste Center at the University of Pennsylvania (source) found evidence of GLP1 agonists significantly depressing the perception of all five basic taste qualities. Interestingly, while all participants in the study experienced a slight decline in their sense of smell, it was not considered statistically significant suggesting that olfactory changes may be more individualised, or more complex to detect in standardised tests
