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65 In this regard, the incretin hormones, namely GIP and GLP-1, represent key targets for the treatment of T2D and obesity, but are also known to play significant roles in bone metabolism, especially in terms of GIP

Vitamin B12 might be the answer

Age Studies show that people who are over the age of 50 may struggle to store vitamin B12 due to a decrease in the production of stomach acid and inflammation of the stomach

Vet Med 51:8188

EGCG can effectively prevent the downregulation of A [53]