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Although the FLOW trial and the secondary analysis of the SELECT trial have demonstrated important kidney benefits of semaglutide, the kidney-protective effects of other GLP-1 receptor agonists are less well known, as there have not been prospective trials with kidney outcomes, and it is unclear whether the benefits of these medications are a class effect or are medication specific

The natural carotenoid astaxanthin, a PPAR- agonist and PPAR- antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid-loaded hepatocytes

doi:10.1155/2021/9458587

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