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Mechanistically, cancer cells capable of inducing cancer cachexia are secreting IL-6, which subsequently induces autophagy in differentiated muscle cells via IL-6 signaling and therefore might be relevant for the characteristic muscle and weight loss during cancer cachexia (276)

For deficiency, B12 shots are given weekly or every other week at first

Compound 2 ml of solution contains active substances: Vitamin B1 (Thiamine Hydrochloride) - 100 mg Vitamin B6 (Pyridoxine Hydrochloride) - 100 mg Vitamin B12 (Cyanocobalamin) - 1 mg, excipients : diethanolamine, water for injection Pharmacological properties Pharmacokinetics The drug contains a combination of B vitamins: thiamine hydrochloride (B1), pyridoxine hydrochloride (B6) and cyanocobalamin (B12)

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Vitamin B12 (cobalamin) is essential for DNA synthesis, myelin formation, and red blood cell maturation