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Despite their relative simplicity, yeast cells generate ROS in the mitochondria through the same mechanisms as mammalian cells and utilize the same thiol redox pathways

[DOI] [PubMed] [Google Scholar] (245).Chang MCY

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Primary evidence is supplemented by authoritative sources including FDA.gov, NIH.gov, MayoClinic.org, and ClevelandClinic.org due to limited recent peer-reviewed publications on this specific query

This is the same compositional logic that underlies other studied combinations in the Durham Peptides catalog pairing compounds with distinct, complementary mechanisms rather than redundant ones

This implies that upstream modulators like KEAP1 may be more important than direct Nrf2 modulation as the primary mechanism 104