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In mice, the ototoxicity could be mitigated or reversed with NAC.[ref] Gastric bleeding: Similar to NSAIDs, acetaminophen can also increase the risk of gastrointestinal bleeding or ulcers

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Beyond 3 months: Continued treatment helps stabilize the results and address any remaining uneven areas, especially for deeper pigmentation

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Jahrestagung der Deutschen Gessellschaft fuer Haematologie und Onkologie, Onkologie 4:278, 1981