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Efflux may affect efficacy of TGR inhibitors ex vivo Compounds 7 - 9 were found to have significant NTS killing activity, but the decrease in GSH/GSSG ratio was attenuated and less adult schistosomicidal activity was observed

Data from a previous study have al- ready showedthe capacity of GA AE in protectingagainst colonic inflammation in rats.10 The oxidative status was evaluated in treated colons by measure- ment of some oxidant and antioxidant reactors

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Dna damage induces downregulation of histone gene expression through the G1 checkpoint pathway