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Evidence has indicated that regulating the gene expression of TRP-1 and TRP-2 by cAMP is directly associated with MITF, which binds to the M-box sequence (AGTCATGTGCT) located in the tyrosinase distal elements (TDEs) after its activation (22)

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10a and b, respectively)

Liver function tests The mean ALT levels of the control and experimental groups were 45.2 3.4 U/L and 64.3 5.1 U/L, respectively, and the difference was statistically significant ( p = 0.001) as indicated by the t -test

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