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At 1.7 mg, nausea prevalence reaches its near-peak

Dulaglutide significantly reduced the risk of this primary composite outcome by 12% compared to placebo (p=0.026)

Tirzepatide, which targets both GLP-1 and GIP receptors, tends to produce similar gastrointestinal side effects but may have different impacts on gut motility patterns

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Your body has completely lost its tolerance to the medication, and jumping to a higher dose will cause severe gastrointestinal symptoms including nausea, vomiting, and potential dehydration