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62 The effector protein is typically pro-caspase-1, an inactive precursor of caspase-1

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However, knockout mice were not protected from hepatic steatosis induced by a high fat diet, potentially due to decreased fatty acid oxidation caused by a compensatory increase of ACC2, which in turn inhibited mitochondrial -oxidation [58]

Calanna, S

Intermediate phase: weeks two through four More noticeable changes typically emerge during weeks two through four