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Mice were dosed every other day for a total of seven treatments, and body weight and food intake were measured daily

Dehydration, can be caused by gastric emptying suppressing the thirst cue as well as the hunger cue, can cause people to not drink fluids throughout the day as they usually would

Elevated ROS levels and activation of the oxidative damage-associated p38 MAPK signaling pathway were also observed in the LCs of premature aging mouse models, with partial restoration of steroidogenic capacity upon treatment with p38 MAPK inhibitors [39]

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GLP-1 acts on insulin secretion and satiety: it increases insulin and decreases glucagon secretion, thereby blocking the endogenous production of glucose and decreasing glycemia after a meal