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Immune-deficient NOD-SCID-IL2RG-/- mice (NSI mice, GIBH) were used as recipients for in vivo transplantation experiments

The livers of mutant rats became markedly dark, whereas the livers of normal rats maintained their typical color

A 2022 analysis of FDA adverse-event reports, published in Frontiers in Endocrinology , identified 2,670 reported cases of acute kidney injury linked to GLP-1 medicines over an 18-year span