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These adverse effects stem from the entry of the cytoplasmic exonuclease TREX1 into the nucleus, which induces DNA cleavage [195], as well as the translocation of DNA repair factors such as Ku70, Ku80, and BRCA1 to the cytoplasm [190, 194]

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human chorionic gonadotropin (hCG)

Detailed human pharmacokinetics have not been characterized

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