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Haemorrhoids are not listed as an adverse reaction in the Wegovy Summary of Product Characteristics (SmPC), and they did not emerge as a significant safety signal during the STEP (Semaglutide Treatment Effect in People with obesity) clinical trial programme
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Additionally, rapid weight loss can alter electrolyte balance, with potential effects on neuromuscular function
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This projection is supported by the broad utility of GLP-1 medications, which not only are effective for weight loss but also improve a range of comorbid conditions associated with obesity, including heart failure, chronic kidney disease, sleep apnea, and fatty liver disease
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