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Have certain medical conditions: Problems that can restrict vitamin B12 absorption include pernicious anemia (a rare autoimmune disease that keeps the body from making a protein necessary to absorb B12), digestive illnesses, such as celiac and Crohns diseases, and immune disorders such as lupus, among others

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Nausea: If you are already experiencing mild nausea from your weight loss medication, adding aspirin may make that sensation more pronounced