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The top six groups of psychiatric AEs with the highest number of reports were insomnia ( n = 1,198, 11.70%), anxiety ( n = 1,131, 11.04%), nervousness ( n = 941, 9.19%), depression ( n = 770, 7.52%), stress ( n = 770, 7.52%), and confusional state ( n = 689, 6.73%)
In a statement to WIRED, a Lilly spokesperson Niki Biro noted that, given its effectiveness, retatrutide is currently being targeted to those with high BMI or with obesity-related complications that require a high degree of weight loss, where the clinical need may be greater. Biro also cautions that retatrutide is an investigational molecule that is legally available only to participants in Lillys clinical trials
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The injection should be administered once weekly on the same day each week, though the specific time of day can be flexible based on patient preference and lifestyle factors
