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Furthermore, WB analysis was conducted on extracts from the aortas of aging mice, showing consistent results with in vitro experiments: increased expression of p-P53 and decreased expression of total P53 after FOXO4-DRI treatment

Glutathione works by inhibiting tyrosinase , the enzyme used in melanin production

Erastin, in conjunction with SLC7A5 and the SLC7A5/SLC3A2 complex, also downregulates the expression of SLC3A2 and SLC7A11, thereby influencing the occurrence of ferroptosis [12, 74, 75]

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Zhang, F