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Mounjaro (Tirzepatide) works by mimicking the actions of two naturally occurring hormones, GIP and GLP-1, that regulate appetite, glucose metabolism, and insulin secretion

Animal studies demonstrate that GLP-1 receptor agonists accumulate in lactating tissue, and while direct human lactation data is sparse, molecular weight and protein-binding characteristics of semaglutide suggest significant milk transfer occurs

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Therefore, different reproductive strategies that aim to enhance the efficiency of estrous synchronization protocols are required to counteract the adverse effects of summer HS, especially on ewes

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PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications