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Likewise, remarkable safety (i.e., LD50 higher than 2000 mg/kg through oral or intravenous route in mice) confirmed no adverse effect in toxicology studies (none of the animals died)
TEM were described to be one of the major drivers of angiogenesis in a mouse model of spontaneous pancreatic cancer (RIP-Tag2) and orthotopic brain tumors (74)
However, it will take time and rigorous scientific inquiry before Dihexa can be considered a standard treatment for primary parkinsonism
doi: 10.1002/jso.20393 121 LiuXKangWLiJLiXYangPShiMet al
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While the exact structure is proprietary to Novo Nordisk, the changes are designed to keep full amylin receptor agonist activity while preventing the aggregation that limits native amylins treatment utility
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