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described 12 EDS patients (six with classic EDS, six with JHS/EDS-HT) with orthostatic intolerance demonstrated by orthostatic stress test [123]

Plasma AST activity may reflect changes in hepatic function in addition to alterations in muscle membrane permeability (Coles, 1986)

The loading efficiency (LE) of SA in MSNs-ss-SA can be calculated using the following formula based on the TGA results: where M 2 is the weight loss of MSNs-ss-NH 2 , and M 3 is the weight loss of MSNs-ss-SA

*Clinical Trial Tested by the 'Cutis Biomedical Research Center' & 'Global Institute of Dermatological Sciences'