Pendulum GLP-1 Probiotic doesn't appear to have been studied in any clinical trials, and we haven't come across any evidence proving that this proprietary formulation increases GLP-1 levels
2024 Study Warns About GLP-1 Gastric Side Effects In the latest study, a group of researchers from Beijing University of Chinese Medicine and the University of Chicago performed a systemic review of 76 studies to evaluate the comparative safety and effectiveness of fifteen different GLP-1 receptor agonists, including semaglutide (Ozempic and Wegovy), tirzepatide (Mounjaro and Zepbound), exenatide (Byetta and Bydureon) and other commonly prescribed brands
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doi: 10.1007/s00125-013-3145-0
And in June 2024, they updated their recommendations, now advising intensive counseling for children aged six and older with a high body mass index (identified as having a BMI at or above the 95th percentile)
Nonetheless, these severe side effects were also present in some people who took GLP-1s and tirzepatide for weight loss and were not suffering from type 2 diabetes