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doi: 10.1007/s00284-024-03775-w 225 JiangPJingSShengGJiaF

[48] Incomplete list of affected drugs [edit] By enzyme [edit] Drugs that interact with grapefruit compounds at CYP3A4 include: benzodiazepines: triazolam (Halcion), orally administered midazolam (Versed), orally administered nitrazepam (Mogodon), diazepam (Valium), [49] clonazepam [50] [51] (Klonopin), alprazolam (Xanax) and quazepam (Doral, Dormalin) [52] ritonavir (Norvir): Inhibition of CYP3A4 prevents the metabolism of protease inhibitors such as ritonavir

doi: 10.1371/journal.pone.0119034

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Many health plans and pharmacy benefit managers (PBMs) have instituted prior authorization to ensure the appropriate use of these medications for FDA-approved uses