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There is a lot of stigma around these medications and staying on them for a long time, especially among patients with obesity, she says, so its very reassuring that the numbers arent going the opposite direction. Sonali Thosani, an endocrinologist at MD Anderson, agreed that its reassuring to see reduced cancer risks with long-term use of these drugs

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Both the SURPASS program (type 2 diabetes) and SURMOUNT program (obesity) reported nausea, diarrhea, and constipation among the most frequent treatment-emergent adverse events, particularly during dose escalation phases

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We gratefully acknowledge and thank the following individuals at NIDDK/DEOB, NIH, USA: K