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The subcutaneous injection introduces a small volume of solution into the tissue beneath the skin, which can cause mechanical tissue distension and activate local nociceptors

Dispose of the pen correctly: After use, discard the pen in a sharps disposal container as instructed

It is important for individuals with a history of mental health conditions to monitor how they feel after starting semaglutide

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This can improve treatment success and adherence

What is more disruptive to the treatment is attempting to take doses at irregular times or in suboptimal conditions, such as taking a missed tablet late in the day when a proper fasting period cannot be guaranteed