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Patients should be aware that while constipation is a common side effect, it is usually manageable with lifestyle adjustments and medical guidance

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Prog Neuro-Psychopharmacol Biol Psychiatry 88:352359 Eshraghi R, Deth RC, Mittal R, Aranke M, Kay S-IS, Moshiree B, Eshraghi A (2018) Early disruption of the microbiome leading to decreased antioxidant capacity and epigenetic changes: implications for the rise in autism

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Community sources frame the 5-on/2-off and 8-week-cycle pattern around cost and letting IGF-1 normalize between blocks