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Reduces corticosterone peaks in hypoxia and restraint models, modeling stress-response pathways

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Critically, GHK-Cu delivers copper as cofactor for lysyl oxidase and lysyl hydroxylase, copper-dependent enzymes essential for collagen cross-linking and stability

Mota J, Casimiro S, Fernandes J, Hartmann RM, Schemitt E, Picada J, Costa L, Marroni N, Raymundo A, Lima A, Ferreira RB

J Cardiovasc Pharmacol 50:647653 Eason RC, Archer HE, Akhtar S, Bailey CJ (2002) Lipoic acid increases glucose uptake by skeletal muscles of obese-diabetic ob/ob mice