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References Berg JM, Tymoczko JL, Stryer L (2002) Glucose 6-Phosphate Dehydrogenase Plays a Key Role in Protection Against Reactive Oxygen Species

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Across all three studies, the most frequently reported adverse events were gastrointestinal in nature and included nausea, vomiting, diarrhea, reduced appetite, and abdominal distension, which were dose-dependent and considered to be mild to moderate in severity [84]

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NICE guidance and UK SmPC recommend individualised prescribing decisions considering HbA1c levels, cardiovascular risk, and digestive function in post-cholecystectomy patients