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Important caveat: Side effect data comes primarily from animal studies

Cardiovascular risk evidence uses the 2.4 mg dose

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Further studies are required to assess the efficacy of use of PRP for therapy and its possible long-term adverse reactions

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What We Do Not Know We lack peer reviewed data defining systemic exposure thresholds, tissue distribution, immunogenicity rates, potential peptide related impurities impact, chronic dosing safety, interaction with existing pathologic angiogenesis (e.g