It is a biological one
Overall satisfied
MARNYSCarnitine 3000formulation includesliposome technology, which allowsL-Carnitine to be easily absorbed in the small intestine, improving its bioavailability and enabling its presence and activity in tissues
This activates protein kinase A (PKA), which phosphorylates and stabilizes MITF (microphthalmia-associated transcription factor), driving transcriptional upregulation of tyrosinase, TRP-1, and TRP-2rate-limiting enzymes in the eumelanin biosynthesis pathway (Abdel-Malek et al., Pigment Cell Research, 2001)
Turco MY, Gardner L, Hughes J, Cindrova-Davies T, Gomez MJ, Farrell L, Hollinshead M, Marsh SGE, Brosens JJ, Critchley HO, Simons BD, Hemberger M, Koo BK, Moffett A, Burton GJ (2017) Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium
6 Conclusion The encouraging results observed in PsO suggest that GLP-1RAs may have broader applications in managing immune-mediated diseases such as PsA