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It is worth noting that these pre-clinical studies were conducted in mice, whose tumor lymphatic drainage and lymphosome are distinct from those of humans

Most patients starting with normal b12 levels and no significant risk factors do not require supplementation

First, the products may be abraded by human handling, diet mixing, or chewing by the animal, which will expose the protected AA to the ruminal microorganism and influence the availability for intestinal absorption

Future research should focus on personalized antioxidant therapy guided by biomarker profiling to optimize clinical outcomes