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For internal hemorrhoids, a digital rectal exam may be performed

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[1] Cell Line:TRX2 -/- DT40 cells (chicken B-cell line) Concentration:1 mM Incubation Time:30 min pretreatment before 1 g/mL Doxycycline induction Result:Reduced activation of caspase-3 and caspase-9, key markers of mitochondrial apoptosis pathway, compared to untreated cells